A client with urge incontinence is prescribed oxybutynin chloride. Which sign may indicate a toxic effect of this medication?

Oxybutynin chloride is an anticholinergic medication used to treat urge incontinence by decreasing bladder spasms. While various side effects can occur with this medication, restlessness may suggest a toxic effect.

Restlessness can indicate central nervous system effects due to anticholinergic properties. When oxybutynin is used, an excess of anticholinergic activity can lead to agitation and restlessness, especially if the dose is too high or if the patient has a sensitivity to anticholinergics. This could signify that the medication is impacting the central nervous system, which may require adjustment of therapy or further evaluation by the healthcare provider.

While dry eyes, constipation, and drowsiness are common side effects associated with oxybutynin use due to its anticholinergic effects, they do not typically indicate toxicity. Dry eyes can be a common and expected side effect without warning of severe complications. Constipation is also a frequent side effect of anticholinergics but does not necessarily reflect toxicity. Drowsiness can occur, but it is more often a benign side effect rather than a sign of overdose or toxicity. Therefore, restlessness stands out as a sign of potential toxicity requiring clinical attention.