After kidney transplantation, which lab result indicates adverse effects from cyclosporine?

Study for the NCLEX Pharmacology Renal and Urinary Exam. Use quizzes and comprehensive questions with explanations to enhance learning. Prepare effectively for your exam!

In the context of kidney transplantation, cyclosporine is commonly used as an immunosuppressant to prevent organ rejection. One of the significant concerns with cyclosporine therapy is its potential nephrotoxic effects. An elevated blood urea nitrogen (BUN) level can indicate impaired kidney function, which may occur as a result of cyclosporine toxicity.

A blood urea nitrogen level of 25 mg/dL suggests that there is an increase in nitrogenous waste products in the blood, indicative of diminished kidney function. This elevation can signal that the kidneys are not properly filtering waste due to potential damage or inadequate blood flow, which could be a direct result of cyclosporine's adverse effects on the kidneys.

In contrast, other options like a BUN level of 12 mg/dL or a creatinine level of 0.5 mg/dL suggest normal kidney function and are not concerning in terms of cyclosporine toxicity. A blood glucose level of 100 mg/dL is also within normal limits and does not directly relate to the nephrotoxic potential of cyclosporine. Therefore, the BUN level of 25 mg/dL accurately reflects a concerning situation indicating adverse effects from cy

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