When would a nurse question the administration of dutasteride for a client?

Dutasteride is a medication used primarily for the treatment of benign prostatic hyperplasia (BPH) in men and works by inhibiting the conversion of testosterone to dihydrotestosterone (DHT). The use of dutasteride in patients with a history of prostate cancer requires careful consideration. This is due to the fact that dutasteride can alter the levels of prostate-specific antigen (PSA), which is a marker used to monitor prostate cancer.

If a patient has a history of prostate cancer, the administration of dutasteride can complicate the assessment and monitoring of the disease. There is a risk that lowering DHT may not be suitable for these patients, as it can mask the progression of prostate cancer by altering PSA levels.

In contrast, other options such as frequent urination, high blood pressure, or allergies to sulfa drugs do not have the same direct contraindication with the use of dutasteride. While frequent urination is a symptom that might lead someone to consider treatment with dutasteride, and high blood pressure might warrant caution with other medications, neither of these directly contraindicates the use of dutasteride. Allergies to sulfa drugs, while important, are not relevant since dutasteride is not