Which electrolyte imbalance can result from the use of loop diuretics?

Study for the NCLEX Pharmacology Renal and Urinary Exam. Use quizzes and comprehensive questions with explanations to enhance learning. Prepare effectively for your exam!

Loop diuretics, such as furosemide, are commonly used to manage conditions like heart failure and edema. They work by inhibiting the reabsorption of sodium and chloride in the ascending loop of Henle in the kidneys, leading to increased urine output. This mechanism often results in various electrolyte imbalances.

Hypocalcemia, which is indicated in your chosen answer, can occur with the use of loop diuretics because these agents not only promote excretion of sodium and potassium but also affect calcium reabsorption. The decreased reabsorption leads to a lower concentration of calcium in the blood, potentially causing hypocalcemia.

While it's true that loop diuretics can lead to other imbalances, such as hyponatremia and hypokalemia, they are less commonly associated with conditions like hyperkalemia and hypermagnesemia. Therefore, hypocalcemia is a well-documented consequence of loop diuretic use and illustrates the need to monitor electrolyte levels closely in patients receiving these medications.

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